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Mechanism of intestinal secretion. Effect of serotonin on rabbit ileal crypt and villus cells.

To determine the mechanism of action of an intestinal secretagogue, serotonin, we have isolated crypt and villus cells and demonstrated Na:H and Cl:HCO3 exchange activity using the intracellular pH-sensitive fluorescent dye, 2,7-bis (carboxy-ethyl)-5,6-carboxy-fluorescein. Serotonin alkalinized both...

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Détails bibliographiques
Publié dans:J Clin Invest
Auteurs principaux: Sundaram, U, Knickelbein, R G, Dobbins, J W
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 1991
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296369/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1991855/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115056
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