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Mechanism of intestinal secretion. Effect of serotonin on rabbit ileal crypt and villus cells.

To determine the mechanism of action of an intestinal secretagogue, serotonin, we have isolated crypt and villus cells and demonstrated Na:H and Cl:HCO3 exchange activity using the intracellular pH-sensitive fluorescent dye, 2,7-bis (carboxy-ethyl)-5,6-carboxy-fluorescein. Serotonin alkalinized both...

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Bibliografiska uppgifter
I publikationen:J Clin Invest
Huvudupphovsmän: Sundaram, U, Knickelbein, R G, Dobbins, J W
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Clinical Investigation 1991
Ämnen:
Länkar:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296369/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1991855/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115056
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