Mechanism of intestinal secretion. Effect of serotonin on rabbit ileal crypt and villus cells.

To determine the mechanism of action of an intestinal secretagogue, serotonin, we have isolated crypt and villus cells and demonstrated Na:H and Cl:HCO3 exchange activity using the intracellular pH-sensitive fluorescent dye, 2,7-bis (carboxy-ethyl)-5,6-carboxy-fluorescein. Serotonin alkalinized both...

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Veröffentlicht in:	J Clin Invest
Hauptverfasser:	Sundaram, U, Knickelbein, R G, Dobbins, J W
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Clinical Investigation 1991
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296369/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1991855/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115056
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