The Efficacy of Pneumococcal Capsular Polysaccharide-specific Antibodies to Serotype 3 Streptococcus pneumoniae requires Macrophages

The efficacy of antibody immunity against Streptococcus pneumoniae stems from the ability of opsonic, serotype (ST)-specific antibodies to pneumococcal capsular polysaccharide (PPS) to facilitate killing of the homologous ST by host phagocytes. However, PPS-specific antibodies have been identified t...

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Bibliographic Details
Main Authors: Fabrizio, Kevin, Manix, Catherine, Tian, Haijun, van Rooijen, Nico, Pirofski, Liise-anne
Format: Artigo
Language:Inglês
Published: 2010
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2963664/
https://ncbi.nlm.nih.gov/pubmed/20800700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2010.08.061
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