Efficacy of Opsonic and Nonopsonic Serotype 3 Pneumococcal Capsular Polysaccharide-Specific Monoclonal Antibodies against Intranasal Challenge with Streptococcus pneumoniae in Mice

Serotype-specific antibodies to pneumococcal capsular polysaccharide (PPS) are a critical component of vaccine-mediated immunity to Streptococcus pneumoniae. In this study, we investigated the in vitro opsonophagocytic activities of three PPS-specific mouse immunoglobulin G1 monoclonal antibodies (M...

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Bibliographic Details
Main Authors: Tian, Haijun, Weber, Sarah, Thorkildson, Peter, Kozel, Thomas R., Pirofski, Liise-anne
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2009
Subjects:
Microbial Immunity and Vaccines
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2663166/
https://ncbi.nlm.nih.gov/pubmed/19168739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01075-08
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