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Drosophila heparan sulfate 6-O endosulfatase regulates Wingless morphogen gradient formation

Heparan sulfate proteoglycans (HSPGs) play critical roles in the distribution and signaling of growth factors, but the molecular mechanisms regulating HSPG function are poorly understood. Here, we characterized Sulf1, which is a Drosophila member of the HS 6-O endosulfatase class of HS modifying enz...

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Detaylı Bibliyografya
Asıl Yazarlar: Kleinschmit, Adam, Koyama, Takashi, Dejima, Katsufumi, Hayashi, Yoshiki, Kamimura, Keisuke, Nakato, Hiroshi
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2010
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2963650/
https://ncbi.nlm.nih.gov/pubmed/20637191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2010.07.006
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