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Drosophila heparan sulfate 6-O endosulfatase regulates Wingless morphogen gradient formation
Heparan sulfate proteoglycans (HSPGs) play critical roles in the distribution and signaling of growth factors, but the molecular mechanisms regulating HSPG function are poorly understood. Here, we characterized Sulf1, which is a Drosophila member of the HS 6-O endosulfatase class of HS modifying enz...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2010
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2963650/ https://ncbi.nlm.nih.gov/pubmed/20637191 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2010.07.006 |
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