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Drosophila heparan sulfate 6-O endosulfatase regulates Wingless morphogen gradient formation

Heparan sulfate proteoglycans (HSPGs) play critical roles in the distribution and signaling of growth factors, but the molecular mechanisms regulating HSPG function are poorly understood. Here, we characterized Sulf1, which is a Drosophila member of the HS 6-O endosulfatase class of HS modifying enz...

詳細記述

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書誌詳細
主要な著者: Kleinschmit, Adam, Koyama, Takashi, Dejima, Katsufumi, Hayashi, Yoshiki, Kamimura, Keisuke, Nakato, Hiroshi
フォーマット: Artigo
言語:Inglês
出版事項: 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2963650/
https://ncbi.nlm.nih.gov/pubmed/20637191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2010.07.006
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