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Identification and Characterization of Bmi-1-responding Element within the Human p16 Promoter
Bmi-1, the first functionally identified polycomb gene family member, plays critical roles in cell cycle regulation, cell immortalization, and cell senescence. Bmi-1 is involved in the development and progression of carcinomas and is a potent target for cancer therapy. One important pathway regulate...
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| Auteurs principaux: | , , , , , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Biochemistry and Molecular Biology
2010
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2963359/ https://ncbi.nlm.nih.gov/pubmed/20551323 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.133686 |
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