Identification and Characterization of Bmi-1-responding Element within the Human p16 Promoter

Bmi-1, the first functionally identified polycomb gene family member, plays critical roles in cell cycle regulation, cell immortalization, and cell senescence. Bmi-1 is involved in the development and progression of carcinomas and is a potent target for cancer therapy. One important pathway regulate...

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Bibliografiske detaljer
Main Authors: Meng, Sha, Luo, Min, Sun, He, Yu, Xin, Shen, Meili, Zhang, Quancang, Zhou, Rudan, Ju, Xiaofang, Tao, Wei, Liu, Di, Deng, Hongkui, Lu, Zhigang
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2010
Fag:
Cell Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2963359/
https://ncbi.nlm.nih.gov/pubmed/20551323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.133686
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