Characterization of hMTr1, a Human Cap1 2′-O-Ribose Methyltransferase

Cellular eukaryotic mRNAs are capped at their 5′ ends with a 7-methylguanosine nucleotide, a structural feature that has been shown to be important for conferring mRNA stability, stimulating mRNA biogenesis (splicing, poly(A) addition, nucleocytoplasmic transport), and increasing translational effic...

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Bibliographic Details
Main Authors: Bélanger, François, Stepinski, Janusz, Darzynkiewicz, Edward, Pelletier, Jerry
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2010
Subjects:
RNA
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2963352/
https://ncbi.nlm.nih.gov/pubmed/20713356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.155283
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