Effect of chronic ethanol feeding on glutathione and functional integrity of mitochondria in periportal and perivenous rat hepatocytes.

Chronic ethanol feeding selectively impairs the translocation of cytosol GSH into the mitochondrial matrix. Since ethanol-induced liver cell injury is preferentially localized in the centrilobular area, we examined the hepatic acinar distribution of mitochondrial GSH transport in ethanol-fed rats. E...

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Dettagli Bibliografici
Pubblicato in:J Clin Invest
Autori principali: García-Ruiz, C, Morales, A, Ballesta, A, Rodés, J, Kaplowitz, N, Fernández-Checa, J C
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 1994
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Research Article
Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296297/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8040260/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117306
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