Effect of chronic ethanol feeding on glutathione and functional integrity of mitochondria in periportal and perivenous rat hepatocytes.

Chronic ethanol feeding selectively impairs the translocation of cytosol GSH into the mitochondrial matrix. Since ethanol-induced liver cell injury is preferentially localized in the centrilobular area, we examined the hepatic acinar distribution of mitochondrial GSH transport in ethanol-fed rats. E...

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Veröffentlicht in:	J Clin Invest
Hauptverfasser:	García-Ruiz, C, Morales, A, Ballesta, A, Rodés, J, Kaplowitz, N, Fernández-Checa, J C
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Clinical Investigation 1994
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296297/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8040260/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117306
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