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The central role of chromatin in autoimmune responses to histones and DNA in systemic lupus erythematosus.

To gain insight into the mechanisms of autoantibody induction, sera from 40 patients with systemic lupus erythematosus (SLE) were tested by ELISAs for antibody binding to denatured individual histones, native histone-histone complexes, histone-DNA subnucleosome complexes, three forms of chromatin, a...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Principais autores: Burlingame, R W, Boey, M L, Starkebaum, G, Rubin, R L
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1994
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296296/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8040259/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117305
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