The central role of chromatin in autoimmune responses to histones and DNA in systemic lupus erythematosus.

To gain insight into the mechanisms of autoantibody induction, sera from 40 patients with systemic lupus erythematosus (SLE) were tested by ELISAs for antibody binding to denatured individual histones, native histone-histone complexes, histone-DNA subnucleosome complexes, three forms of chromatin, a...

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Veröffentlicht in:	J Clin Invest
Hauptverfasser:	Burlingame, R W, Boey, M L, Starkebaum, G, Rubin, R L
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Clinical Investigation 1994
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296296/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8040259/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117305
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