Homologies between T cell receptor junctional sequences unique to multiple sclerosis and T cells mediating experimental allergic encephalomyelitis.

The selection of T cell clones with mutations in the hypoxanthine guanine phosphoribosyltransferase (hprt) gene has been used to isolate T cells reactive to myelin basic protein (MBP) in patients with multiple sclerosis (MS). These T cell clones are activated in vivo, and are not found in healthy in...

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Allegretta, M, Albertini, R J, Howell, M D, Smith, L R, Martin, R, McFarland, H F, Sriram, S, Brostoff, S, Steinman, L
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 1994
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296287/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8040252/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117295
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