In healthy primates, circulating autoreactive T cells mediate autoimmune disease.

A T cell response against myelin basic protein (MBP) is thought to contribute to the central nervous system (CNS) inflammation that occurs in the human demyelinating disease multiple sclerosis. To test whether MBP-reactive T cells that are normally retrieved from the circulation are capable of induc...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Genain, C P, Lee-Parritz, D, Nguyen, M H, Massacesi, L, Joshi, N, Ferrante, R, Hoffman, K, Moseley, M, Letvin, N L, Hauser, S L
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1994
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC295221/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7521889/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117454
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