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In healthy primates, circulating autoreactive T cells mediate autoimmune disease.

A T cell response against myelin basic protein (MBP) is thought to contribute to the central nervous system (CNS) inflammation that occurs in the human demyelinating disease multiple sclerosis. To test whether MBP-reactive T cells that are normally retrieved from the circulation are capable of induc...

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Détails bibliographiques
Auteurs principaux: Genain, C P, Lee-Parritz, D, Nguyen, M H, Massacesi, L, Joshi, N, Ferrante, R, Hoffman, K, Moseley, M, Letvin, N L, Hauser, S L
Format: Artigo
Langue:Inglês
Publié: 1994
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC295221/
https://ncbi.nlm.nih.gov/pubmed/7521889
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