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In healthy primates, circulating autoreactive T cells mediate autoimmune disease.

A T cell response against myelin basic protein (MBP) is thought to contribute to the central nervous system (CNS) inflammation that occurs in the human demyelinating disease multiple sclerosis. To test whether MBP-reactive T cells that are normally retrieved from the circulation are capable of induc...

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Pubblicato in:J Clin Invest
Autori principali: Genain, C P, Lee-Parritz, D, Nguyen, M H, Massacesi, L, Joshi, N, Ferrante, R, Hoffman, K, Moseley, M, Letvin, N L, Hauser, S L
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 1994
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC295221/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7521889/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117454
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