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In healthy primates, circulating autoreactive T cells mediate autoimmune disease.

A T cell response against myelin basic protein (MBP) is thought to contribute to the central nervous system (CNS) inflammation that occurs in the human demyelinating disease multiple sclerosis. To test whether MBP-reactive T cells that are normally retrieved from the circulation are capable of induc...

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Sparad:
I publikationen:J Clin Invest
Huvudupphov: Genain, C P, Lee-Parritz, D, Nguyen, M H, Massacesi, L, Joshi, N, Ferrante, R, Hoffman, K, Moseley, M, Letvin, N L, Hauser, S L
Materialtyp: Artigo
Språk:Inglês
Utgiven: American Society for Clinical Investigation 1994
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC295221/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7521889/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117454
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