Extensions, Validation, and Clinical Applications of a Feedback Control System Simulator of the Hypothalamo-Pituitary-Thyroid Axis

BACKGROUND: We upgraded our recent feedback control system (FBCS) simulation model of human thyroid hormone (TH) regulation to include explicit representation of hypothalamic and pituitary dynamics, and updated TH distribution and elimination (D&E) parameters. This new model greatly expands the...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Eisenberg, Marisa, Samuels, Mary, DiStefano, Joseph J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Mary Ann Liebert, Inc. 2008
Schlagworte:
Original Studies, Reviews and Scholarly Dialog Thyroid Economy: Regulation, Cell Biology, Thyroid Hormone Metabolism and Action
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2962855/
https://ncbi.nlm.nih.gov/pubmed/18844475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/thy.2007.0388
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