Extensions, Validation, and Clinical Applications of a Feedback Control System Simulator of the Hypothalamo-Pituitary-Thyroid Axis

BACKGROUND: We upgraded our recent feedback control system (FBCS) simulation model of human thyroid hormone (TH) regulation to include explicit representation of hypothalamic and pituitary dynamics, and updated TH distribution and elimination (D&E) parameters. This new model greatly expands the...

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Autors principals: Eisenberg, Marisa, Samuels, Mary, DiStefano, Joseph J.
Format: Artigo
Idioma:Inglês
Publicat: Mary Ann Liebert, Inc. 2008
Matèries:
Original Studies, Reviews and Scholarly Dialog Thyroid Economy: Regulation, Cell Biology, Thyroid Hormone Metabolism and Action
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2962855/
https://ncbi.nlm.nih.gov/pubmed/18844475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/thy.2007.0388
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