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A feedback-controlled ensemble model of the stress-responsive hypothalamo-pituitary-adrenal axis

The present work develops and implements a biomathematical statement of how reciprocal connectivity drives stress-adaptive homeostasis in the corticotropic (hypothalamo-pituitary-adrenal) axis. In initial analyses with this interactive construct, we test six specific a priori hypotheses of mechanism...

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Detalhes bibliográficos
Main Authors: Keenan, Daniel M., Licinio, Julio, Veldhuis, Johannes D.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC31173/
https://ncbi.nlm.nih.gov/pubmed/11274427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.051624198
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