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An Evaluation of Statistical Approaches to Rare Variant Analysis in Genetic Association Studies

Genome-wide association (GWA) studies have proved to be extremely successful in identifying novel common polymorphisms contributing effects to the genetic component underlying complex traits. Nevertheless, one source of, as yet, undiscovered genetic determinants of complex traits are those mediated...

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Detalles Bibliográficos
Main Authors: Morris, Andrew P, Zeggini, Eleftheria
Formato: Artigo
Idioma:Inglês
Publicado: Wiley Subscription Services, Inc., A Wiley Company 2010
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2962811/
https://ncbi.nlm.nih.gov/pubmed/19810025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.20450
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