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CCRaVAT and QuTie - enabling analysis of rare variants in large-scale case control and quantitative trait association studies

BACKGROUND: Genome-wide association studies have been successful in finding common variants influencing common traits. However, these associations only account for a fraction of trait heritability. There has been a shift in the field towards studying low frequency and rare variants, which are now wi...

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Autors principals: Lawrence, Robert, Day-Williams, Aaron G, Elliott, Katherine S, Morris, Andrew P, Zeggini, Eleftheria
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2973964/
https://ncbi.nlm.nih.gov/pubmed/20964851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-11-527
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