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Genetics and complement in atypical HUS
Central to the pathogenesis of atypical hemolytic uremic syndrome (aHUS) is over-activation of the alternative pathway of complement. Following the initial discovery of mutations in the complement regulatory protein, factor H, mutations have been described in factor I, membrane cofactor protein and...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Springer-Verlag
2010
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2962786/ https://ncbi.nlm.nih.gov/pubmed/20526633 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00467-010-1555-5 |
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