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aHUS caused by complement dysregulation: new therapies on the horizon

Atypical hemolytic uremic syndrome (aHUS) is a heterogeneous disease that is caused by defective complement regulation in over 50% of cases. Mutations have been identified in genes encoding both complement regulators [complement factor H (CFH), complement factor I (CFI), complement factor H-related...

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Detalhes bibliográficos
Main Authors: Waters, Aoife M., Licht, Christoph
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2991208/
https://ncbi.nlm.nih.gov/pubmed/20556434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00467-010-1556-4
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