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Application of a Chiral Scaffolding Ligand in Catalytic Enantioselective Hydroformylation

The synthesis of β-amino-aldehydes has been achieved through enantioselective hydroformylation of PMP-protected allylic amines. The reaction is accomplished by using a scalemic scaffolding ligand that covalently and reversibly binds to the substrate. These ligands behave like chiral auxiliaries beca...

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Détails bibliographiques
Auteurs principaux: Worthy, Amanda D., Joe, Candice L., Lightburn, Thomas E., Tan, Kian L.
Format: Artigo
Langue:Inglês
Publié: 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2962579/
https://ncbi.nlm.nih.gov/pubmed/20882977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja107433h
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