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Allostery Is an Intrinsic Property of the Protease Domain of DegS: IMPLICATIONS FOR ENZYME FUNCTION AND EVOLUTION

DegS is a periplasmic Escherichia coli protease, which functions as a trimer to catalyze the initial rate-limiting step in a proteolytic cascade that ultimately activates transcription of stress response genes in the cytoplasm. Each DegS subunit consists of a protease domain and a PDZ domain. During...

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Detalles Bibliográficos
Main Authors: Sohn, Jungsan, Grant, Robert A., Sauer, Robert T.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2962503/
https://ncbi.nlm.nih.gov/pubmed/20739286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.135541
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