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A conserved activation cluster is required for allosteric communication in HtrA-family proteases
In E. coli, outer-membrane stress causes a transcriptional response through a signaling cascade initiated by DegS cleavage of a transmembrane anti-sigma factor. Each subunit of DegS, an HtrA-family protease, contains a protease domain and a PDZ domain. The trimeric protease domain is autoinhibited b...
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| Publicado no: | Structure |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4351158/ https://ncbi.nlm.nih.gov/pubmed/25703375 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2015.01.012 |
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