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Adiponectin-induced ERK and Akt Phosphorylation Protects against Pancreatic Beta Cell Apoptosis and Increases Insulin Gene Expression and Secretion

The functional impact of adiponectin on pancreatic beta cells is so far poorly understood. Although adiponectin receptors (AdipoR1/2) were identified, their involvement in adiponectin-induced signaling and other molecules involved is not clearly defined. Therefore, we investigated the role of adipon...

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Detalhes bibliográficos
Main Authors: Wijesekara, Nadeeja, Krishnamurthy, Mansa, Bhattacharjee, Alpana, Suhail, Aamir, Sweeney, Gary, Wheeler, Michael B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2962460/
https://ncbi.nlm.nih.gov/pubmed/20709750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.085084
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