Activity of individual ERCC1 and XPF subunits in DNA nucleotide excision repair
ERCC1–XPF is a structure-specific nuclease with two subunits, ERCC1 and XPF. The enzyme cuts DNA at junctions where a single strand moves 5′ to 3′ away from a branch point with duplex DNA. This activity has a central role in nucleotide excision repair (NER), DNA cross-link repair and recombination....
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| Veröffentlicht in: | Nucleic Acids Res |
|---|---|
| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2001
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC29621/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11160918/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/29.4.872 |
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