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Activity of individual ERCC1 and XPF subunits in DNA nucleotide excision repair

ERCC1–XPF is a structure-specific nuclease with two subunits, ERCC1 and XPF. The enzyme cuts DNA at junctions where a single strand moves 5′ to 3′ away from a branch point with duplex DNA. This activity has a central role in nucleotide excision repair (NER), DNA cross-link repair and recombination....

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Bibliografiska uppgifter
Huvudupphovsmän: Gaillard, Pierre-Henri L., Wood, Richard D.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2001
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC29621/
https://ncbi.nlm.nih.gov/pubmed/11160918
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