Novel Antibacterial Class

We report the discovery and characterization of a novel ribosome inhibitor (NRI) class that exhibits selective and broad-spectrum antibacterial activity. Compounds in this class inhibit growth of many gram-positive and gram-negative bacteria, including the common respiratory pathogens Streptococcus...

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Detalhes bibliográficos
Main Authors: Dandliker, Peter J., Pratt, Steve D., Nilius, Angela M., Black-Schaefer, Candace, Ruan, Xiaoan, Towne, Danli L., Clark, Richard F., Englund, Erika E., Wagner, Rolf, Weitzberg, Moshe, Chovan, Linda E., Hickman, Robert K., Daly, Melissa M., Kakavas, Stephan, Zhong, Ping, Cao, Zhensheng, David, Caroline A., Xuei, Xiaoling, Lerner, Claude G., Soni, Niru B., Bui, Mai, Shen, Linus L., Cai, Yingna, Merta, Philip J., Saiki, Anne Y. C., Beutel, Bruce A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Mechanisms of Action: Physiological Effects
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC296205/
https://ncbi.nlm.nih.gov/pubmed/14638491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.12.3831-3839.2003
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