Polymorphism in the 3′-untranslated region of TNFα mRNA impairs binding of the post-transcriptional regulatory protein HuR to TNFα mRNA

Tumor necrosis factor α (TNFα) acts as a beneficial mediator in the process of host defence. In recent years major interest has focused on the AU-rich elements (AREs) present in the 3′-untranslated region (3′-UTR) of TNFα mRNA as this region plays a pivotal role in post-transcriptional control of TN...

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הוצא לאור ב:	Nucleic Acids Res
Principais autores:	Di Marco, Sergio, Hel, Zdenek, Lachance, Claude, Furneaux, Henry, Radzioch, Danuta
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	Oxford University Press 2001
נושאים:	Article
גישה מקוונת:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC29616/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11160917/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/29.4.863
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