Intravenous Inoculation of Replication-Deficient Recombinant Vaccinia Virus DIs Expressing Simian Immunodeficiency Virus Gag Controls Highly Pathogenic Simian-Human Immunodeficiency Virus in Monkeys

To be effective, a vaccine against human immunodeficiency virus type 1 (HIV-1) must induce virus-specific T-cell responses and it must be safe for use in humans. To address these issues, we developed a recombinant vaccinia virus DIs vaccine (rDIsSIVGag), which is nonreplicative in mammalian cells an...

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Vydáno v:	J Virol
Hlavní autoři:	Izumi, Yasuyuki, Ami, Yasushi, Matsuo, Kazuhiro, Someya, Kenji, Sata, Tetsutaro, Yamamoto, Naoki, Honda, Mitsuo
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology (ASM) 2003
Témata:	Vaccines and Antiviral Agents
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296093/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14645581/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.24.13248-13256.2003
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