Intravenous Inoculation of Replication-Deficient Recombinant Vaccinia Virus DIs Expressing Simian Immunodeficiency Virus Gag Controls Highly Pathogenic Simian-Human Immunodeficiency Virus in Monkeys

To be effective, a vaccine against human immunodeficiency virus type 1 (HIV-1) must induce virus-specific T-cell responses and it must be safe for use in humans. To address these issues, we developed a recombinant vaccinia virus DIs vaccine (rDIsSIVGag), which is nonreplicative in mammalian cells an...

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Main Authors: Izumi, Yasuyuki, Ami, Yasushi, Matsuo, Kazuhiro, Someya, Kenji, Sata, Tetsutaro, Yamamoto, Naoki, Honda, Mitsuo
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2003
Assuntos:
Vaccines and Antiviral Agents
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC296093/
https://ncbi.nlm.nih.gov/pubmed/14645581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.24.13248-13256.2003
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