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Structural analysis of the binding modes of minor groove ligands comprised of disubstituted benzenes

Two-dimensional homonuclear NMR was used to characterize synthetic DNA minor groove-binding ligands in complexes with oligonucleotides containing three different A-T binding sites. The three ligands studied have a C(2) axis of symmetry and have the same general structural motif of a central para-sub...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Principais autores: Hawkins, Cheryl A., Watson, Charles, Yan, Yinfa, Gong, Bing, Wemmer, David E.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC29609/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11160926/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/29.4.936
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