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Characterization of rabbit ileal receptors for Clostridium difficile toxin A. Evidence for a receptor-coupled G protein.

The purpose of this study was to characterize the surface receptor for toxin A, the enterotoxin from Clostridium difficile, on rabbit intestinal brush borders (BB) and on rat basophilic leukemia (RBL) cells. Purified toxin A was radiolabeled using a modified Bolton-Hunter method to sp act 2 microCi/...

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Опубликовано в::J Clin Invest
Главные авторы: Pothoulakis, C, LaMont, J T, Eglow, R, Gao, N, Rubins, J B, Theoharides, T C, Dickey, B F
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Clinical Investigation 1991
Предметы:
Online-ссылка:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296011/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1905325/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115267
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