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Characterization of rabbit ileal receptors for Clostridium difficile toxin A. Evidence for a receptor-coupled G protein.

The purpose of this study was to characterize the surface receptor for toxin A, the enterotoxin from Clostridium difficile, on rabbit intestinal brush borders (BB) and on rat basophilic leukemia (RBL) cells. Purified toxin A was radiolabeled using a modified Bolton-Hunter method to sp act 2 microCi/...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Pothoulakis, C, LaMont, J T, Eglow, R, Gao, N, Rubins, J B, Theoharides, T C, Dickey, B F
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1991
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296011/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1905325/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115267
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