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Characterization of rabbit ileal receptors for Clostridium difficile toxin A. Evidence for a receptor-coupled G protein.

The purpose of this study was to characterize the surface receptor for toxin A, the enterotoxin from Clostridium difficile, on rabbit intestinal brush borders (BB) and on rat basophilic leukemia (RBL) cells. Purified toxin A was radiolabeled using a modified Bolton-Hunter method to sp act 2 microCi/...

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Bibliografiske detaljer
Udgivet i:J Clin Invest
Principais autores: Pothoulakis, C, LaMont, J T, Eglow, R, Gao, N, Rubins, J B, Theoharides, T C, Dickey, B F
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 1991
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296011/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1905325/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115267
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