Germ line transcription of the immunoglobulin heavy chain locus directs production of mu chain without VDJ.
Immunoglobulin VDJ recombination is associated with transcriptional activation of the Ig variable region elements. We have previously described a novel Ig mu chain protein and mRNA produced by pre-B cell hybrids from normal and X-linked agammaglobulinemic bone marrow. We have now characterized the m...
Guardat en:
| Publicat a: | J Clin Invest |
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| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Clinical Investigation
1992
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC295921/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1602010/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115816 |
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