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Germ line transcription of the immunoglobulin heavy chain locus directs production of mu chain without VDJ.

Immunoglobulin VDJ recombination is associated with transcriptional activation of the Ig variable region elements. We have previously described a novel Ig mu chain protein and mRNA produced by pre-B cell hybrids from normal and X-linked agammaglobulinemic bone marrow. We have now characterized the m...

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Détails bibliographiques
Publié dans:J Clin Invest
Auteurs principaux: Schwaber, J, Malone, B
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 1992
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC295921/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1602010/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115816
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