Disease and gender-specific dysregulation of NGAL and MMP-9 in type 1 diabetes mellitus

Neutrophil gelatinase-associated lipocalin (NGAL), a biomarker of renal injury, can bind matrix metalloproteinase-9 (MMP-9) and inhibit its degradation, thereby sustaining MMP-9 proteolytic activity. MMP-9 is produced by renal podocytes, and podocyte MMP production can be modified by high ambient gl...

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Bibliografiska uppgifter
Huvudupphovsmän: Thrailkill, Kathryn M., Moreau, Cynthia S., Cockrell, Gael E., Jo, Chan-Hee, Bunn, Robert C., Morales-Pozzo, Alba E., Lumpkin, Charles K., Fowlkes, John L.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2010
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2959192/
https://ncbi.nlm.nih.gov/pubmed/20960272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12020-010-9308-6
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