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Disease and gender-specific dysregulation of NGAL and MMP-9 in type 1 diabetes mellitus
Neutrophil gelatinase-associated lipocalin (NGAL), a biomarker of renal injury, can bind matrix metalloproteinase-9 (MMP-9) and inhibit its degradation, thereby sustaining MMP-9 proteolytic activity. MMP-9 is produced by renal podocytes, and podocyte MMP production can be modified by high ambient gl...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2959192/ https://ncbi.nlm.nih.gov/pubmed/20960272 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12020-010-9308-6 |
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