PGC-1α Regulates Expression of Myocardial Mitochondrial Antioxidants and Myocardial Oxidative Stress After Chronic Systolic Overload

Mitochondria are a principal site for generation of reactive oxygen species (ROS) in the heart. Peroxisome proliferator activated receptor γ coactivator 1α (PGC-1α) plays an important role in regulating mitochondrial biogenesis and myocardial metabolism, but whether PGC-1α can simultaneously upregul...

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Autors principals: Lu, Zhongbing, Xu, Xin, Hu, Xinli, Fassett, John, Zhu, Guangshuo, Tao, Yi, Li, Jingxin, Huang, Yimin, Zhang, Ping, Zhao, Baolu, Chen, Yingjie
Format: Artigo
Idioma:Inglês
Publicat: Mary Ann Liebert, Inc. 2010
Matèries:
Original Research Communications
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2959178/
https://ncbi.nlm.nih.gov/pubmed/20406135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2009.2940
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