IL-16 Promotes T. whipplei Replication by Inhibiting Phagosome Conversion and Modulating Macrophage Activation

The replication of Tropheryma whipplei (the agent of Whipple's disease) within human macrophages is associated with the expression of IL-16, a cytokine known for its chemotactic and inflammatory properties. In this study, we asked whether IL-16 acts on T. whipplei replication by interfering wit...

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Bibliographic Details
Main Authors: Ghigo, Eric, Barry, Abdoulaye Oury, Pretat, Lionel, Al Moussawi, Khatoun, Desnues, Benoît, Capo, Christian, Kornfeld, Hardy, Mege, Jean-Louis
Format: Artigo
Language:Inglês
Published: Public Library of Science 2010
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2958842/
https://ncbi.nlm.nih.gov/pubmed/21042409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0013561
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