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Potentiation of tubuloglomerular feedback in the rat by thromboxane mimetic. Role of macula densa.

Because endogenous thromboxane A2 (TXA2) potentiates the tubuloglomerular feedback response (TGF), we studied the mechanism of action of TXA2 by using a stable TXA2/prostaglandin (PG) H2 mimetic, U-46,619. Intravenous infusion of U-46,619 at 100 ng.kg-1.min-1 reduced the GFR and the single-nephron (...

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Bibliografiske detaljer
Udgivet i:J Clin Invest
Principais autores: Welch, W J, Wilcox, C S
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 1992
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC295884/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1601993/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115790
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