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Potentiation of tubuloglomerular feedback in the rat by thromboxane mimetic. Role of macula densa.

Because endogenous thromboxane A2 (TXA2) potentiates the tubuloglomerular feedback response (TGF), we studied the mechanism of action of TXA2 by using a stable TXA2/prostaglandin (PG) H2 mimetic, U-46,619. Intravenous infusion of U-46,619 at 100 ng.kg-1.min-1 reduced the GFR and the single-nephron (...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Clin Invest
Auteurs principaux: Welch, W J, Wilcox, C S
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 1992
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC295884/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1601993/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115790
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