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Potentiation of tubuloglomerular feedback in the rat by thromboxane mimetic. Role of macula densa.

Because endogenous thromboxane A2 (TXA2) potentiates the tubuloglomerular feedback response (TGF), we studied the mechanism of action of TXA2 by using a stable TXA2/prostaglandin (PG) H2 mimetic, U-46,619. Intravenous infusion of U-46,619 at 100 ng.kg-1.min-1 reduced the GFR and the single-nephron (...

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Autors principals: Welch, W J, Wilcox, C S
Format: Artigo
Idioma:Inglês
Publicat: 1992
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC295884/
https://ncbi.nlm.nih.gov/pubmed/1601993
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