Evaluation of Soluble Junctional Adhesion Molecule-A as a Biomarker of Human Brain Endothelial Barrier Breakdown

BACKGROUND: An inducible release of soluble junctional adhesion molecule-A (sJAM-A) under pro-inflammatory conditions was described in cultured non-CNS endothelial cells (EC) and increased sJAM-A serum levels were found to indicate inflammation in non-CNS vascular beds. Here we studied the regulatio...

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Main Authors: Haarmann, Axel, Deiß, Annika, Prochaska, Jürgen, Foerch, Christian, Weksler, Babette, Romero, Ignacio, Couraud, Pierre-Olivier, Stoll, Guido, Rieckmann, Peter, Buttmann, Mathias
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2958838/
https://ncbi.nlm.nih.gov/pubmed/21060661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0013568
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