Immunomodulatory effects of therapeutic gold compounds. Gold sodium thiomalate inhibits the activity of T cell protein kinase C.

Previous studies have shown that the gold compounds, gold sodium thiomalate (GST) and auranofin (AUR), which are effective in the treatment of rheumatoid arthritis, inhibit functional activities of a variety of cells, but the biochemical basis of their effect is unknown. In the current studies, huma...

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Hashimoto, K, Whitehurst, C E, Matsubara, T, Hirohata, K, Lipsky, P E
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 1992
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC295882/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1351061/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115788
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