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Immunomodulatory effects of therapeutic gold compounds. Gold sodium thiomalate inhibits the activity of T cell protein kinase C.

Previous studies have shown that the gold compounds, gold sodium thiomalate (GST) and auranofin (AUR), which are effective in the treatment of rheumatoid arthritis, inhibit functional activities of a variety of cells, but the biochemical basis of their effect is unknown. In the current studies, huma...

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Opis bibliograficzny
Wydane w:J Clin Invest
Główni autorzy: Hashimoto, K, Whitehurst, C E, Matsubara, T, Hirohata, K, Lipsky, P E
Format: Artigo
Język:Inglês
Wydane: American Society for Clinical Investigation 1992
Hasła przedmiotowe:
Dostęp online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC295882/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1351061/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115788
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